Grillo is a white grape variety that is renowned for its role in Marsala winemking. Crisp and fruity dry Grillo wines are gaining popularity in recent years. Originating from Sicily, it is now grown in various regions around the world.

Grillo produces light to medium bodied wines with a light greenish-yellow colour. The aroma and flavour profile consists of citrus and stone fruit, floral and herbal notes, with a touch of salinty.

Grillo is mainly grown in west coast of Sicily, where it is used as a component of Marsala, and also in Puglia. It is grown in small quantities in Argentina, Australia, Malta, California, New Zealand and South Africa. Grillo is a vigorous variety and it is sensitive to powdery and downy mildew. It can tolerate drought and has low susceptibility to botrytis. The winemaking process typically involves stainless steel fermentation, but oak barrels are sometimes used, depending on the desired style. In Sicily, Grillo is used to make fresh and flavorful varietal wines, as well as Marsala, a fortified wine. Some Sicilian producers often blend it with Chardonnay, to make easy-drinking table whites. Grillo's fresh acidity and fruity flavours make it a great accompaniment to seafood dishes, salads and light pastas.

Grillo is the Italian word for cricket and it is believed that the variety was named after the insect because of its song-like buzzing noise.